Measures of Association (Measures of Effect)

Odds Ratio (OR)

This is the odds of a person with a disease to have been exposed to a risk factor vs. the odds of a person without the 

disease being exposed to that same risk factor. This is used in retrospective studies.

Example. Smoking (exposure) vs. Lung Cancer (outcome)

Outcome- Lung Cancer 

No Outcome-No Cancer

Total

Exposure –Smoking

15

45

60

No Exposure- No Smoking

6

24

30

OR=Odds of someone with cancer having smoked/ Odds of someone without cancer having smoked= (15/45)/(6/24)= (24*15)/(45*6)=1.33

This would be calculated for a case control study (retrospective design).