SQUAMOUS CARCINOMA OF EPIGLOTTIS, 22628
22628 SQUAMOUS CARCINOMA OF EPIGLOTTIS
This patient was a man aged 64 who had smoked 30 cigarettes/day for 40 years. For the last 3 months there had been a productive cough with mucoid sputum. This was followed by pain in the left side of the chest, breathlessness, and a small haemoptysis. X-ray showed a shadow in the left upper lobe. On examination the left upper lobe was consolidated and there was a left pleural effusion. The sputum and pleural aspirate were positive for malignant cells. Surgery and radiotherapy were felt to he contra-indicated and he was treated by repeated aspiration of the pleural fluid and instillation of nitrogen mustard. He died after 4 weeks in hospital. At postmortem massive right bronchogenic carcinoma was found spreading to the supraclavicular nodes, mediastinal nodes, the liver and the right adrenal. In addition a tumour was found in the posterior surface of the epiglottis.
The specimen is of the base of the tongue, the larynx, and upper trachea opened from behind to display a nodular fungating carcinoma 2 cms in diameter arising from the body of the epiglottis and projecting posteriorly over the entrance to the larynx. Inferiorly the tumour extends downwards to within half a centimetre of the left false vocal cord. Histology shows a well differentiated squamous-cell carcinoma.